Description

n-[(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Yliden)Methyl]-3-(Trifluoromethyl)Benzenecarboxamide is a specialized organic compound featuring a unique dioxane-dione scaffold coupled with a trifluoromethylbenzamide group. This molecular architecture makes it a valuable advanced intermediate for the synthesis of complex active ingredients, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries who require high-purity, structurally complex building blocks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the biological activity of the trifluoromethyl and dioxanedione motifs.
• Chemical Biology Probe: Acts as a scaffold for creating molecular probes to study biological pathways and protein functions in academic and industrial research settings.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical entity.

Basic Information

Product Name	n-[(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Yliden)Methyl]-3-(Trifluoromethyl)Benzenecarboxamide
CAS No.	477885-72-6
Molecular Formula	C16H14F3NO5
Molecular Weight	357.28 g/mol
Synonyms	5-[[[3-(Trifluoromethyl)benzoyl]amino]methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione; 3-(Trifluoromethyl)-N-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]benzamide; Meldrum's acid derivative of 3-(trifluoromethyl)benzamide; TFMB-Meldrum's acid adduct; (Z)-5-((3-(Trifluoromethyl)benzamido)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
EINECS	Contact for details

Quality Control

Every batch of n-[(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Yliden)Methyl]-3-(Trifluoromethyl)Benzenecarboxamide is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.