Description

n-[(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Yliden)Methyl]-4-Fluorobenzenecarboxamide is a high-purity, specialized organic intermediate featuring a reactive dioxane-dione (Meldrum's acid derivative) scaffold coupled with a fluorinated benzamide moiety. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly within pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries seeking to incorporate its unique structural elements into new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated bioactive components.
• Agrochemical Research: Used in developing new herbicides, fungicides, or insecticides where the fluorobenzene and reactive dioxanedione groups can impart specific biological activity and stability.
• Chemical Biology Probe Development: Acts as a versatile scaffold for creating molecular probes and tools to study enzyme mechanisms or protein interactions in biological systems.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with tailored degradation profiles or functional properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis, particularly involving Meldrum's acid derivatives and fluorinated compounds.

Basic Information

Product Name	n-[(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Yliden)Methyl]-4-Fluorobenzenecarboxamide
CAS No.	477885-71-5
Molecular Formula	C15H14FNO5
Molecular Weight	307.27 g/mol
Synonyms	5-[(4-Fluorobenzamido)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione; 4-Fluoro-N-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]benzamide; Meldrum's acid derivative, fluorinated; (4-Fluorobenzoylaminomethylene) Meldrum's acid; 2,2-Dimethyl-5-[(4-fluorobenzoylamino)methylene]-1,3-dioxane-4,6-dione; Fluorobenzamido Meldrum's Acid Derivative; CAS 477885-71-5
EINECS	Contact for details

Quality Control

Our n-[(2,2-Dimethyl-4,6-Dioxo-1,3-Dioxan-5-Yliden)Methyl]-4-Fluorobenzenecarboxamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and may be moisture-sensitive; prolonged exposure to air or humidity should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.