Description

2-[(4-Bromophenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile is a high-value, multi-functional organic intermediate featuring a bromophenyl sulfide linkage and a trifluoromethyl benzonitrile core. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure imparts specific electronic and steric properties. It is primarily needed by research and development teams, as well as production chemists, in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted functionalities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced polymers, liquid crystals, or organic semiconductors for electronic applications.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study enzyme function or protein-protein interactions in biochemical research.
• Cross-Coupling Reactions: The bromophenyl moiety makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl systems.

Basic Information

Product Name	2-[(4-Bromophenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile
CAS No.	477867-11-1
Molecular Formula	C14H7BrF3NS
Molecular Weight	358.18 g/mol
Synonyms	5-(Trifluoromethyl)-2-[(4-bromophenyl)thio]benzonitrile; 2-((4-Bromophenyl)thio)-5-(trifluoromethyl)benzonitrile; 4-Bromo-α,α,α-trifluoro-2'-(methylthio)[1,1'-biphenyl]-3-carbonitrile; Benzonitrile, 2-[(4-bromophenyl)thio]-5-(trifluoromethyl)-; [477867-11-1]
EINECS	Contact for details

Quality Control

Our 2-[(4-Bromophenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.