Description

2-[(2-Methylphenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile is a high-value, multi-functional organic intermediate featuring a benzonitrile core with a trifluoromethyl group and a methylphenylthioether substituent. This compound is engineered to provide a versatile and reactive scaffold for advanced synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed as a versatile synthon in academic and industrial laboratories for methodology development and exploring new chemical spaces in medicinal and synthetic chemistry.
• Ligand and Catalyst Development: The sulfur and nitrogen functionalities make it a candidate for constructing novel ligands used in transition metal catalysis.

Basic Information

Product Name	2-[(2-Methylphenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile
CAS No.	477866-93-6
Molecular Formula	C15H10F3NS
Molecular Weight	293.31 g/mol
Synonyms	2-[(2-Methylphenyl)thio]-5-(trifluoromethyl)benzonitrile; 5-(Trifluoromethyl)-2-[(o-tolyl)thio]benzonitrile; 2-(o-Tolylthio)-5-(trifluoromethyl)benzonitrile; 2-[(2-Methylphenyl)sulfanyl]-5-(trifluoromethyl)benzonitrile; 2-(2-Methylphenylsulfanyl)-5-trifluoromethylbenzonitrile; Benzonitrile, 2-[(2-methylphenyl)thio]-5-(trifluoromethyl)-; 477866-93-6
EINECS	Contact for details

Quality Control

Our production of 2-[(2-Methylphenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.