Description

6-Acetyl-2-[3-(Trifluoromethyl)Phenyl]-1,2,4-Triazine-3,5(2H,4H)-Dione is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a triazinedione scaffold with acetyl and trifluoromethylphenyl substituents, making it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients. Its specific structure offers a strategic handle for introducing key pharmacophores and modulating the physicochemical properties of target compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science: Investigated as a monomer or additive for creating high-performance polymers with specific thermal or optical properties.
• Chemical Biology Probe: Utilized in academic and industrial research to design molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical building block for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Acetyl-2-[3-(Trifluoromethyl)Phenyl]-1,2,4-Triazine-3,5(2H,4H)-Dione
CAS No.	477854-36-7
Molecular Formula	C₁₂H₈F₃N₃O₃
Molecular Weight	299.21 g/mol
Synonyms	6-Acetyl-2-[3-(trifluoromethyl)phenyl]-1,2,4-triazine-3,5(2H,4H)-dione; 2-(3-Trifluoromethylphenyl)-6-acetyl-1,2,4-triazine-3,5-dione; 1,2,4-Triazine-3,5(2H,4H)-dione, 6-acetyl-2-[3-(trifluoromethyl)phenyl]-; 6-Acetyl-2-(3-trifluoromethylphenyl)-1,2,4-triazine-3,5-dione; 477854-36-7; α-Acetyl-2-(α,α,α-trifluoro-m-tolyl)-1,2,4-triazine-3,5(2H,4H)-dione
EINECS	Contact for details

Quality Control

Our production of 6-Acetyl-2-[3-(Trifluoromethyl)Phenyl]-1,2,4-Triazine-3,5(2H,4H)-Dione adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.