Description

Cyclohexanecarbonitrile, 1-Hydroxy-4-Methoxy-, trans- (9Ci) is a specialized, high-purity organic intermediate with a defined stereochemistry. This compound matters for its role as a critical building block in the synthesis of complex molecules, offering precise structural control for advanced research and development. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and fine chemical manufacturers developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the specific stereochemistry can influence biological activity and environmental profile.
• Liquid Crystal & OLED Material Research: Serves as a precursor for synthesizing chiral dopants and charge-transport materials in display and optoelectronic applications.
• Asymmetric Catalysis Ligand Precursor: Provides a scaffold for developing novel chiral ligands and organocatalysts used in enantioselective synthesis.
• Flavor & Fragrance Ingredient Synthesis: Employed in the creation of complex, high-value aroma chemicals with specific olfactory characteristics.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, particularly in stereochemistry and nitrile chemistry.

Basic Information

Product Name	Cyclohexanecarbonitrile, 1-Hydroxy-4-Methoxy-, trans- (9Ci)
CAS No.	477344-80-2
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	trans-1-Hydroxy-4-methoxycyclohexanecarbonitrile; (1r,4r)-4-Methoxycyclohexane-1-carbonitrile; 4-Methoxycyclohexanecarbonitrile, 1-hydroxy-, trans-; 1-Hydroxy-4-methoxy-cyclohexanecarbonitrile; trans-4-Methoxy-1-hydroxycyclohexanecarbonitrile; (trans)-1-Hydroxy-4-methoxycyclohexanecarbonitrile; 1-Hydroxy-4-methoxycyclohexanecarbonitrile (trans isomer); CAS 477344-80-2
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonitrile, 1-Hydroxy-4-Methoxy-, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.