Description

1-(4-Fluorophenyl)-3-[(4-Fluorophenyl)Sulfonyl]-1-Propanone is a high-purity, fluorinated aromatic sulfone building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorophenyl sulfone group can contribute to biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Ligand and Catalyst Development: Utilized as a precursor for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-[(4-Fluorophenyl)Sulfonyl]-1-Propanone
CAS No.	477334-49-9
Molecular Formula	C15H12F2O3S
Molecular Weight	310.32 g/mol
Synonyms	1-Propanone, 1-(4-fluorophenyl)-3-[(4-fluorophenyl)sulfonyl]-; 3-[(4-Fluorophenyl)sulfonyl]-1-(4-fluorophenyl)-1-propanone; 4-Fluoro-β-(4-fluorobenzenesulfonyl)propiophenone; 1,1'-[Sulfonylbis(4,1-phenylene)]bis-3-propanone Fluorinated Derivative; 4,4'-Difluorodiphenyl Sulfone Propiophenone Derivative
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-3-[(4-Fluorophenyl)Sulfonyl]-1-Propanone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.