Description

3-[(4-Fluorophenyl)Sulfanyl]-1-(2-Naphthyl)-1-Propanone is a specialized organic building block featuring a unique naphthyl ketone core linked via a propanone bridge to a fluorinated phenylsulfanyl moiety. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the development of complex molecules with tailored electronic and steric properties. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom and sulfur linkage can enhance biological activity and environmental stability.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, or organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	3-[(4-Fluorophenyl)Sulfanyl]-1-(2-Naphthyl)-1-Propanone
CAS No.	477334-39-7
Molecular Formula	C19H15FOS
Molecular Weight	310.39 g/mol
Synonyms	1-(Naphthalen-2-yl)-3-[(4-fluorophenyl)thio]propan-1-one; 3-(4-Fluorophenylthio)-1-(2-naphthyl)-1-propanone; 1-(2-Naphthyl)-3-[(4-fluorophenyl)thio]-1-propanone; 3-(p-Fluorophenylthio)-1-(2-naphthyl)propan-1-one; 477334-39-7; 3-[(4-Fluorophenyl)thio]-1-(2-naphthyl)propan-1-one
EINECS	Contact for details

Quality Control

Our production of 3-[(4-Fluorophenyl)Sulfanyl]-1-(2-Naphthyl)-1-Propanone adheres to stringent in-process and final release controls to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles against agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.