Description

1-(4-Fluorophenyl)-3-[4-(Trifluoromethyl)Anilino]-1-Propanone is a high-value, fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters because its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts desirable properties like metabolic stability and enhanced lipophilicity, making it a critical intermediate for research and development. It is primarily needed by pharmaceutical, agrochemical, and advanced material scientists for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Active Ingredient Synthesis: Used to develop new generations of herbicides and pesticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for fluorinated polymers and liquid crystals, contributing to materials with unique thermal and chemical resistance.
• Chemical Biology Probe Development: Utilized in creating labeled compounds and probes for studying biological pathways and protein interactions.
• Organic Electronics: Investigated as a component in the synthesis of organic semiconductors and electron-transport materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-[4-(Trifluoromethyl)Anilino]-1-Propanone
CAS No.	477334-16-0
Molecular Formula	C16H13F4NO
Molecular Weight	311.28 g/mol
Synonyms	1-Propanone, 1-(4-fluorophenyl)-3-[[4-(trifluoromethyl)phenyl]amino]-; 3-((4-(Trifluoromethyl)phenyl)amino)-1-(4-fluorophenyl)propan-1-one; N-[4-(Trifluoromethyl)phenyl]-3-oxo-3-(4-fluorophenyl)propylamine; 1-(4-Fluorophenyl)-3-(4-trifluoromethylanilino)-1-propanone; 477334-16-0; FC-APAP Derivative Intermediate; Fluorinated Anilino Propanone Intermediate
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-3-[4-(Trifluoromethyl)Anilino]-1-Propanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.