Description

Methyl 2-Methyl-2-[4-(Trifluoromethyl)Phenyl]Propanoate is a high-value trifluoromethylated ester building block, prized for its ability to impart unique physicochemical properties to advanced molecules. Its core value proposition lies in providing a sterically hindered, electron-deficient aromatic moiety that is critical for modulating the biological activity and stability of target compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes due to its aromatic and fluorinated structure.
• Polymer Modification: Employed to introduce fluorinated phenyl groups into polymer chains, altering surface properties, chemical resistance, and thermal stability.
• Advanced Material Research: Utilized in academic and industrial R&D for creating novel fluorinated compounds with tailored properties for specialized applications.

Basic Information

Product Name	Methyl 2-Methyl-2-[4-(Trifluoromethyl)Phenyl]Propanoate
CAS No.	476429-18-2
Molecular Formula	C12H13F3O2
Molecular Weight	246.23 g/mol
Synonyms	Methyl 2-(4-(Trifluoromethyl)phenyl)-2-methylpropanoate; 2-Methyl-2-[4-(trifluoromethyl)phenyl]propanoic Acid Methyl Ester; α,α-Dimethyl-4-(trifluoromethyl)benzeneacetic Acid Methyl Ester; Methyl α,α-Dimethyl-4-(trifluoromethyl)phenylacetate; 4-(Trifluoromethyl)hydratropic Acid Methyl Ester; Methyl 4'-(Trifluoromethyl)hydratropate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Methyl-2-[4-(Trifluoromethyl)Phenyl]Propanoate adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.