Description

4-Methoxybenzo[B]Thiophene-2-Carbonitrile is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its functionalized thiophene core, which serves as a key precursor for the development of complex molecules with tailored electronic and biological properties. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene moiety.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Dye and Pigment Chemistry: Acts as an intermediate in the production of specialized dyes and pigments with specific light-absorption properties.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry, including cyclization and cross-coupling reactions.

Basic Information

Item	Details
Product Name	4-Methoxybenzo[B]Thiophene-2-Carbonitrile
CAS No.	476199-13-0
Molecular Formula	C10H7NOS
Molecular Weight	189.23 g/mol
Synonyms	4-Methoxybenzo[b]thiophene-2-carbonitrile; 4-Methoxy-1-benzothiophene-2-carbonitrile; 2-Cyano-4-methoxybenzo[b]thiophene; 4-Methoxybenzo[b]thien-2-yl cyanide; 4-Methoxy-2-cyanobenzo[b]thiophene; 4-Methoxy-2-thianaphthenecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Methoxybenzo[B]Thiophene-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.