Description

1H-Pyrrole-2-Carboxylicacid,4-Fluoro-,Methylester(9Ci) is a high-value fluorinated pyrrole derivative, a crucial building block in advanced organic synthesis. Its core value lies in enabling the precise introduction of a fluorinated heterocyclic scaffold, which is instrumental in modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides, where the fluoropyrrole moiety can enhance efficacy and environmental profile.
• Material Science Research: Acts as a precursor for functionalized polymers, organic semiconductors, and liquid crystals due to its electron-rich pyrrole core and fluorine substituent.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Product Name	1H-Pyrrole-2-Carboxylicacid,4-Fluoro-,Methylester(9Ci)
CAS No.	475561-89-8
Molecular Formula	C6H6FNO2
Molecular Weight	143.12 g/mol
Synonyms	Methyl 4-fluoro-1H-pyrrole-2-carboxylate; 4-Fluoro-1H-pyrrole-2-carboxylic acid methyl ester; 4-Fluoropyrrole-2-carboxylic acid methyl ester; 4-Fluoro-2-(methoxycarbonyl)-1H-pyrrole; 1H-Pyrrole-2-carboxylic acid, 4-fluoro-, methyl ester; Methyl 4-fluoropyrrole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2-Carboxylicacid,4-Fluoro-,Methylester(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.