Description

4-Cyanomethoxy-Phenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl compounds found in drug discovery and development.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands and organometallic catalysts.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Cyanomethoxy-Phenylboronic Acid, Pinacol Ester
CAS No.	475272-13-0
Molecular Formula	C15H20BNO3
Molecular Weight	273.14 g/mol
Synonyms	4-(Cyanomethoxy)phenylboronic acid pinacol ester; [4-(Cyanomethoxy)phenyl]boronic acid pinacol ester; Pinacol [4-(Cyanomethoxy)phenyl]boronate; 4-Cyanomethoxyphenylboronic Acid Pinacol Ester; B-[4-(Cyanomethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-[4-(cyanomethoxy)phenyl]-1,3,2-dioxaborolane; CAS 475272-13-0
EINECS	Contact for details

Quality Control

Our 4-Cyanomethoxy-Phenylboronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.