Description

Piperidine-3-Carboxylic Acid Methyl Amide, Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. This compound is valued for its role as a key chiral precursor in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its piperidine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed in medicinal chemistry to design and synthesize peptide analogs with improved stability and bioavailability.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring high-purity, complex heterocyclic compounds.

Basic Information

Product Name	Piperidine-3-Carboxylic Acid Methyl Amide, Hydrochloride
CAS No.	475060-42-5
Molecular Formula	C8H17ClN2O
Molecular Weight	192.69 g/mol
Synonyms	3-(Methylcarbamoyl)piperidine hydrochloride; Methyl 3-piperidinecarboxylate amide hydrochloride; (3-Piperidinyl)-N-methylcarboxamide hydrochloride; 3-Carbamoylpiperidine, N-methyl-, hydrochloride; Nipecotamide, N-methyl-, hydrochloride; 1-Methyl-3-piperidinecarboxamide hydrochloride; 3-(N-Methylaminocarbonyl)piperidine HCl
EINECS	Contact for details

Quality Control

Our Piperidine-3-Carboxylic Acid Methyl Amide, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and conformity to client specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.