Description

n-[12-[(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)Amino]Dodecanoyl]-D-Galactosyl-1-1'-Sphingosine is a sophisticated, fluorescently labeled glycosphingolipid derivative, specifically designed for advanced biochemical research. This compound matters as a critical tool for the visualization and tracking of sphingolipid metabolism, membrane dynamics, and cellular trafficking pathways. It is primarily needed by researchers and developers in academic institutions, pharmaceutical R&D, and biotechnology companies focused on lipidomics, cell biology, and the development of diagnostic probes.

Application

• Fluorescent Labeling Agent: Used as a vital probe for labeling and imaging sphingolipids in live-cell and fixed-cell microscopy studies.
• Lipid Metabolism Research: Enables the tracking of glycosphingolipid synthesis, degradation, and intracellular transport in metabolic studies.
• Membrane Biology Studies: Applied to investigate lipid raft formation, membrane fluidity, and the role of sphingolipids in cell signaling.
• Drug Discovery Tool: Serves as a substrate or tracer in high-throughput screening assays targeting enzymes involved in sphingolipid pathways.
• Diagnostic Probe Development: Utilized in the research and development of fluorescent diagnostic kits for metabolic disorders.
• Biochemical Standard: Acts as a reference standard in analytical methods like HPLC and mass spectrometry for lipid identification and quantification.

Basic Information

Product Name	n-[12-[(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)Amino]Dodecanoyl]-D-Galactosyl-1-1'-Sphingosine
CAS No.	474942-98-8
Molecular Formula	C₄₆H₇₇N₅O₁₂
Molecular Weight	904.13 g/mol
Synonyms	NBD C12-Galactosylceramide; NBD-GalCer; 6-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl-Galactosyl-β1-1'-sphingosine; Galactocerebroside NBD C12; Fluorescent Galactosylceramide; N-[12-[(7-Nitro-4-benzofurazanyl)amino]dodecanoyl]-D-galactosylsphingosine; NBD-labeled Galactosylsphingosine; NBD C12-GalCer
EINECS	Contact for details

Quality Control

This high-purity biochemical is manufactured under strict quality control protocols to ensure batch-to-batch consistency for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and fluorescence properties are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC)	Conforms to reference standard
Identification (Mass Spec)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, chloroform, DMF
Fluorescence Properties	Ex/Em ~465/535 nm (in lipid membrane)
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.