Description

1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-(Dodecanoyl) (Sodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a functionalized phosphatidylethanolamine (PE). This compound is critical for creating advanced, stable lipid-based delivery systems due to its unique amphiphilic structure. It is an essential raw material for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing next-generation nanomedicines and diagnostic agents.

Application

• Lipid Nanoparticle (LNP) Formulation: A key functional excipient for constructing stable, targeted LNPs used in mRNA vaccines, siRNA delivery, and other nucleic acid therapeutics.
• Liposome & Niosome Development: Used to engineer the surface properties of vesicles for enhanced drug encapsulation, controlled release, and improved circulation time in vivo.
• Biomimetic Membrane Research: Serves as a critical component in model membrane systems (e.g., supported lipid bilayers) for studying cell membrane mechanics, protein-lipid interactions, and biosensor development.
• Targeted Drug Delivery: The functionalizable headgroup allows for conjugation with targeting ligands (e.g., antibodies, peptides) to create cell-specific delivery vehicles for chemotherapeutic agents.
• Diagnostic Imaging Agents: Incorporated into contrast agent carriers for medical imaging techniques such as MRI and ultrasound, improving stability and biodistribution.
• Cosmetic & Dermal Formulations: Used in high-end cosmetic products as a biocompatible emulsifier and penetration enhancer for active ingredients.

Basic Information

Product Name	1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-(Dodecanoyl) (Sodium Salt)
CAS No.	474923-49-4
Molecular Formula	C53H103NNaO9P
Molecular Weight	960.34 g/mol
Synonyms	16:0-12:0 N-Dodecanoyl PE (Sodium Salt); 1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine-N-dodecanoyl (Sodium Salt); N-Dodecanoyl-DPPE (Na Salt); DPPE-C12:0 (Sodium Salt); Functionalized DPPE; N-Acyl PE (16:0/12:0); Sodium 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dodecanoyl
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-(Dodecanoyl) (Sodium Salt) is manufactured under strict quality systems suitable for pharmaceutical R&D and GMP applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and critical impurities. We ensure consistent high purity (typically >98% by HPLC) and batch-to-batch reproducibility to meet the stringent requirements of formulation development and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and water uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Phase Transition Temperature (DSC)	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.