Description

2-(4-Trifluoromethoxybenzylidene)-Malononitrile is a specialized organic compound featuring a benzylidene-malononitrile core functionalized with a trifluoromethoxy group. This molecular architecture makes it a valuable building block and intermediate in advanced chemical synthesis, particularly for applications requiring specific electronic and steric properties. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Organic Electronic Materials: Acts as an electron-accepting unit in the design of organic semiconductors, non-linear optical (NLO) materials, and dyes for sensitized solar cells.
• Chemical Synthesis Building Block: Employed in Knoevenagel condensation and cyclization reactions to construct complex heterocyclic frameworks, such as pyridines and pyrimidines.
• Polymer Chemistry: Can be incorporated as a functional monomer to impart specific properties like hydrophobicity or altered refractive index to advanced polymer systems.
• Academic & Industrial R&D: A crucial reagent for methodological studies in organic chemistry and for exploring structure-activity relationships (SAR) in material science.

Basic Information

Product Name	2-(4-Trifluoromethoxybenzylidene)-Malononitrile
CAS No.	474759-76-7
Molecular Formula	C₁₁H₅F₃N₂O
Molecular Weight	238.17 g/mol
Synonyms	2-[(4-Trifluoromethoxy)benzylidene]malononitrile; 2-(4-(Trifluoromethoxy)benzylidene)malononitrile; 4-Trifluoromethoxybenzylidenemalononitrile; (4-Trifluoromethoxybenzylidene)malononitrile; 2-(4-Trifluoromethoxybenzylidene)propanedinitrile; α-(4-Trifluoromethoxybenzylidene)malononitrile; Propanedinitrile, 2-[(4-(trifluoromethoxy)phenyl)methylene]-; TFMB-MN
EINECS	Contact for details

Quality Control

Our 2-(4-Trifluoromethoxybenzylidene)-Malononitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.