Description

[3-(4-Fluorophenyl)-1H-Pyrazol-4-Yl]Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a versatile building block for constructing complex molecules via cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials. Its specific structure makes it a critical component in the synthesis of targeted chemical libraries and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the Suzuki coupling for efficient scaffold construction.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, polymers, and liquid crystals through palladium-catalyzed cross-coupling.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A key reagent for custom synthesis houses and CROs/CMOs producing bespoke compounds for client R&D programs.
• Academic & Industrial R&D: Fundamental reagent in medicinal chemistry and process chemistry laboratories for exploring new synthetic routes and optimizing reaction conditions.

Basic Information

Product Name	[3-(4-Fluorophenyl)-1H-Pyrazol-4-Yl]Boronic Acid
CAS No.	474711-98-3
Molecular Formula	C9H8BFN2O2
Molecular Weight	205.98 g/mol
Synonyms	4-(4-Fluorophenyl)-1H-pyrazole-5-boronic acid; (3-(4-Fluorophenyl)-1H-pyrazol-4-yl)boronic acid; 3-(4-Fluorophenyl)-1H-pyrazole-4-boronic acid; 4-Borono-3-(4-fluorophenyl)-1H-pyrazole; B-[3-(4-Fluorophenyl)-1H-pyrazol-4-yl]boronic acid; 474711-98-3; AKOS005258030
EINECS	Contact for details

Quality Control

Our [3-(4-Fluorophenyl)-1H-Pyrazol-4-Yl]Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to consistent quality and traceability supports your R&D and production needs with reliable, specification-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.