Description

1,2-Benzenedicarbonitrile,5-Ethoxy-3-Fluoro-4-Methoxy-(9Ci) is a high-purity, fluorinated aromatic dinitrile compound serving as a sophisticated chemical intermediate. Its value lies in its unique molecular architecture, which provides a versatile scaffold for constructing complex molecules in advanced research and manufacturing. This product is essential for R&D chemists and process developers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials. The compound's specific substitution pattern makes it a critical building block for creating compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom and dinitrile group enhance bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes for industrial chemical processes.
• Advanced Material Research: Employed in the development of organic electronic materials, such as components for OLEDs or photovoltaic cells, due to its electron-deficient aromatic core.
• Fluorinated Building Block: A versatile synthon for introducing both fluorine and cyano functional groups into more complex molecular architectures in medicinal and synthetic chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.

Basic Information

Product Name	1,2-Benzenedicarbonitrile,5-Ethoxy-3-Fluoro-4-Methoxy-(9Ci)
CAS No.	474554-36-4
Molecular Formula	C11H9FN2O2
Molecular Weight	220.20 g/mol
Synonyms	5-Ethoxy-3-fluoro-4-methoxyphthalonitrile; 3-Fluoro-5-ethoxy-4-methoxy-1,2-benzenedicarbonitrile; 4-Methoxy-5-ethoxy-3-fluorophthalonitrile; 3-Fluoro-4-methoxy-5-ethoxypththalonitrile; 1,2-Dicyano-5-ethoxy-3-fluoro-4-methoxybenzene; 5-Ethoxy-3-fluoro-4-methoxybenzene-1,2-dicarbonitrile
EINECS	Contact for details

Quality Control

Our 1,2-Benzenedicarbonitrile,5-Ethoxy-3-Fluoro-4-Methoxy-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material is suitable for demanding applications in pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents, strong bases, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.