Description

D-Ribofuranoside, Methyl 5-Deoxy-5-[(1-Oxo-2-Propenyl)Amino]- (9Ci) is a specialized carbohydrate derivative, a modified ribofuranoside with a reactive acrylamido functional group. This compound is of significant interest as a key synthetic intermediate or building block in advanced organic synthesis and medicinal chemistry. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, nucleoside analogs, and bioactive probes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel nucleoside-based drug candidates, including potential antiviral or anticancer agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new bioactive molecules targeting specific enzymes or receptors.
• Bioconjugation Chemistry: The acrylamido group enables its use in Michael addition reactions for labeling or conjugating biomolecules like proteins or oligonucleotides.
• Chemical Biology Probes: Acts as a precursor for synthesizing activity-based probes (ABPs) to study carbohydrate-processing enzymes.
• Academic & Industrial R&D: Employed in exploratory research for developing new synthetic methodologies and novel chemical entities.
• Nucleoside Analog Synthesis: A key starting material for creating modified nucleosides with altered biological properties.

Basic Information

Product Name	D-Ribofuranoside, Methyl 5-Deoxy-5-[(1-Oxo-2-Propenyl)Amino]- (9Ci)
CAS No.	474105-04-9
Molecular Formula	C10H15NO6
Molecular Weight	245.23 g/mol
Synonyms	Methyl 5-Deoxy-5-acrylamido-D-ribofuranoside; 5-Deoxy-5-acrylamido-D-ribofuranoside methyl ester; 5-Acrylamido-5-deoxy-1,2-O-isopropylidene-α-D-ribofuranose (related protected form); Acrylamido-modified ribofuranoside; N-Acryloyl-5-amino-5-deoxy-D-ribofuranoside methyl ester; CAS 474105-04-9
EINECS	Contact for details

Quality Control

Our D-Ribofuranoside, Methyl 5-Deoxy-5-[(1-Oxo-2-Propenyl)Amino]- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere at -20°C to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.