Description

2-Bromo-4-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl and bromo groups impart desirable biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in cross-coupling reactions and other transition metal-catalyzed processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where fluorine substitution modifies electronic properties and stability.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethyl)Phenylacetonitrile
CAS No.	474024-36-7
Molecular Formula	C9H5BrF3N
Molecular Weight	264.04 g/mol
Synonyms	2-Bromo-α-(trifluoromethyl)benzeneacetonitrile; (2-Bromo-4-(trifluoromethyl)phenyl)acetonitrile; 2-Bromo-4-(trifluoromethyl)benzyl cyanide; α-Bromo-4-(trifluoromethyl)phenylacetonitrile; 4-Trifluoromethyl-2-bromophenylacetonitrile; Benzeneacetonitrile, 2-bromo-α-(trifluoromethyl)-; 474024-36-7
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(Trifluoromethyl)Phenylacetonitrile is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.