Description

(4-Trifluoromethylphenyl)Phosphine is a specialized organophosphorus compound featuring a trifluoromethylphenyl substituent, which imparts unique electronic and steric properties. This compound matters as a versatile ligand and building block in advanced chemical synthesis, particularly valued for its ability to modulate catalyst activity and selectivity in challenging transformations. It is needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for applications ranging from cross-coupling catalysis to the development of novel functional materials.

Application

• As a ligand in transition metal catalysis, particularly for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira).
• As a key precursor or intermediate in pharmaceutical research for the synthesis of active pharmaceutical ingredients (APIs).
• In agrochemical development for creating novel pesticides and herbicides with enhanced properties.
• For the synthesis of specialized polymers and advanced materials, including ligands for metal-organic frameworks (MOFs).
• In organic light-emitting diode (OLED) and electronic material research as a building block for charge-transport materials.
• As a reagent in organometallic chemistry studies to explore new reaction pathways and catalytic systems.

Basic Information

Product Name	(4-Trifluoromethylphenyl)Phosphine
CAS No.	473808-83-2
Molecular Formula	C7H6F3P
Molecular Weight	178.09 g/mol
Synonyms	4-(Trifluoromethyl)phenylphosphine; (4-Trifluoromethylphenyl)phosphane; p-Trifluoromethylphenylphosphine; (α,α,α-Trifluoro-p-tolyl)phosphine; Phosphinous acid, P-[4-(trifluoromethyl)phenyl]-; 1-Phosphino-4-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our (4-Trifluoromethylphenyl)Phosphine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing the specific results are provided with every shipment. We are committed to meeting the stringent requirements of research and development as well as cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. Due to its sensitivity to oxidation and light, prolonged exposure to air or ambient light should be avoided. Keep the container in a cool, dry, well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.