Description

4-[4-(Trifluoromethyl)Phenyl]Oxane-4-Carbonitrile is a high-value, fluorinated organic building block characterized by its unique oxane (tetrahydropyran) ring and electron-withdrawing nitrile group. This compound matters for its role as a versatile intermediate in advanced synthetic chemistry, enabling the development of novel molecular architectures with tailored properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by material scientists exploring specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorinated liquid crystals for high-performance displays.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce rigidity and specific polarity into specialty polymer backbones.
• Organic Electronics: Investigated as a building block for electron-transport materials in organic light-emitting diodes (OLEDs) and photovoltaic cells.
• Chemical Research: Employed in academic and industrial R&D for methodology development and exploring structure-activity relationships (SAR).

Basic Information

Product Name	4-[4-(Trifluoromethyl)Phenyl]Oxane-4-Carbonitrile
CAS No.	473706-06-8
Molecular Formula	C13H12F3NO
Molecular Weight	255.24 g/mol
Synonyms	4-[4-(Trifluoromethyl)phenyl]tetrahydro-2H-pyran-4-carbonitrile; 4-(4-(Trifluoromethyl)phenyl)tetrahydro-2H-pyran-4-carbonitrile; 4-(4-Trifluoromethylphenyl)tetrahydropyran-4-carbonitrile; 4-Cyano-4-(4-trifluoromethylphenyl)tetrahydropyran; Tetrahydro-2H-pyran-4-carbonitrile, 4-[4-(trifluoromethyl)phenyl]-; 4-(α,α,α-Trifluoro-p-tolyl)tetrahydropyran-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-[4-(Trifluoromethyl)Phenyl]Oxane-4-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.