Description

(5-Fluorobenzofuran-2-Yl)Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and advanced functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, including herbicides and fungicides.
• Material Science Research: Serves as a building block for developing organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and sensors for diagnostic and research applications.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs and fine chemical producers specializing in fluorinated heterocycles.

Basic Information

Product Name	(5-Fluorobenzofuran-2-Yl)Boronic Acid
CAS No.	473416-33-0
Molecular Formula	C8H6BFO3
Molecular Weight	179.94 g/mol
Synonyms	5-Fluoro-2-benzofuranboronic Acid; 5-Fluorobenzofuran-2-boronic Acid; (5-Fluoro-1-benzofuran-2-yl)boronic Acid; 2-(5-Fluorobenzofuran-2-yl)boronic Acid; B-(5-Fluoro-2-benzofuranyl)boronic Acid; 5-Fluoro-2-furanboronic Acid Benzofused; 5-Fluorobenzo[b]furan-2-ylboronic Acid; 473416-33-0
EINECS	Contact for details

Quality Control

Every batch of (5-Fluorobenzofuran-2-Yl)Boronic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) specifying purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.