Description

Di-(2-Pyridyl)(Diphenylphosphino)Amine is a specialized, nitrogen-phosphorus hybrid ligand with a unique electronic and steric profile, making it a valuable tool in advanced catalytic systems. Its significance lies in its ability to facilitate challenging cross-coupling and other transition metal-catalyzed reactions, offering chemists a pathway to synthesize complex molecules with high efficiency and selectivity. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to develop new synthetic routes and optimize production processes for high-value intermediates and active ingredients.

Application

• As a ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig amination).
• For the development of homogeneous catalysts for C-H activation and functionalization.
• In asymmetric catalysis for the synthesis of chiral pharmaceutical intermediates.
• As a key component in catalyst screening libraries for drug discovery and process research.
• For academic and industrial R&D in organometallic chemistry and new methodology development.
• In the synthesis of specialty polymers and materials with tailored properties.

Basic Information

Product Name	Di-(2-Pyridyl)(Diphenylphosphino)Amine
CAS No.	472959-76-5
Molecular Formula	C22H18N3P
Molecular Weight	355.37 g/mol
Synonyms	Di(2-pyridyl)(diphenylphosphino)amine; N-(Diphenylphosphino)-N,N-di(2-pyridyl)amine; (Diphenylphosphino)bis(2-pyridyl)amine; DPPA; Di(2-pyridyl)aminodiphenylphosphine; N,N-Di(2-pyridyl)-P,P-diphenylphosphinous amide; 2,2'-(Phenylphosphanylideneamino)dipyridine
EINECS	Contact for details

Quality Control

Every batch of Di-(2-Pyridyl)(Diphenylphosphino)Amine is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive catalytic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). Due to its sensitivity to oxidation, the container should be purged with inert gas before resealing after each use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.