Description

(1S,1S',2R,2R')-(+)-1,1'-Di-T-Butyl-[2,2']-Diphospholane CAS NO 470480-32-1 is a high-purity, chiral diphospholane ligand widely used in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in critical transition metal-catalyzed reactions, enabling the production of optically active intermediates. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and effective ligands for hydrogenation and other asymmetric transformations.

Application

• As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines.
• Catalyst component in the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• Enabling technology for creating agrochemicals with specific stereochemistry.
• Key reagent in academic and industrial R&D for developing new catalytic methodologies.
• Used in the preparation of specialty and performance chemicals requiring precise chiral control.

Basic Information

Product Name	(1S,1S',2R,2R')-(+)-1,1'-Di-T-Butyl-[2,2']-Diphospholane
CAS No.	470480-32-1
Molecular Formula	C14H28P2
Molecular Weight	258.31 g/mol
Synonyms	(+)-1,1'-Di-tert-butyl-[2,2']-diphospholane; (S,S,R,R)-Diphospholane DTB-Diphospholane; (1S,1'S,2R,2'R)-1,1'-Di-tert-butyl-2,2'-biphospholane; t-Bu-BIP; DTBPhos; Josiphos-type ligand analog; Chiral bidentate phosphine ligand
EINECS	Contact for details

Quality Control

Every batch of our (1S,1S',2R,2R')-(+)-1,1'-Di-T-Butyl-[2,2']-Diphospholane is produced and tested under strict quality management systems. We ensure high chiral purity and chemical integrity through advanced analytical techniques including NMR, HPLC, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters are provided to guarantee batch-to-batch consistency for your catalytic processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.