Description

n-(5-Iodo-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide is a high-purity, iodinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyridine core for biological activity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes and protein interactions.
• Material Science: A building block for organic electronic materials and photoactive compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthetic projects requiring iodinated heterocycles.

Basic Information

Product Name	n-(5-Iodo-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide
CAS No.	470463-36-6
Molecular Formula	C10H13IN2O
Molecular Weight	304.13 g/mol
Synonyms	2,2-Dimethyl-N-(5-iodopyridin-2-yl)propanamide; 5-Iodo-2-pivalamidopyridine; N-(5-Iodo-2-pyridinyl)-2,2-dimethylpropanamide; Pivalamide, N-(5-iodo-2-pyridinyl)-; Propanamide, 2,2-dimethyl-N-(5-iodo-2-pyridinyl)-; 470463-36-6; 5-Iodo-N-(pyridin-2-yl)pivalamide
EINECS	Contact for details

Quality Control

Our n-(5-Iodo-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.