Description

Elsilimomab is a monoclonal antibody designed for targeted therapeutic intervention. This compound is of significant interest in advanced pharmaceutical research and development due to its specific mechanism of action. It is primarily utilized by biotechnology and pharmaceutical companies engaged in the development of novel immunotherapies and treatments for complex diseases. The product is supplied under stringent quality controls to ensure consistency for critical research and pre-clinical applications.

Application

• Immunotherapy Research: A key reagent for studying immune system modulation and developing targeted biological therapies.
• Pre-clinical Development: Used in animal model studies to evaluate efficacy, pharmacokinetics, and safety profiles of antibody-based treatments.
• Mechanism of Action Studies: Essential for in vitro assays to understand specific binding interactions and downstream cellular effects.
• Biopharmaceutical Reference Standard: Serves as a high-purity reference material for analytical method development and quality control in bioprocessing.
• Diagnostic Assay Development: Potential use as a capture or detection antibody in the development of sensitive immunoassays.

Basic Information

Product Name	Elsilimomab
CAS No.	468715-71-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Anti-IL-6 Receptor Monoclonal Antibody; B-E8; Monoclonal Antibody B-E8; Anti-IL-6R mAb; IL6R mAb; Immunoglobulin G1, anti-(human interleukin 6 receptor) (human-mouse monoclonal B-E8 γ1-chain), disulfide with human-mouse monoclonal B-E8 κ-chain, dimer
EINECS	Contact for details

Quality Control

Our Elsilimomab is produced and tested under a rigorous quality management system. Each batch is characterized for identity, purity, potency, and consistency using advanced analytical techniques such as HPLC, SDS-PAGE, and ELISA. We provide comprehensive Certificates of Analysis (COA) with detailed results for all critical quality attributes, ensuring it meets the exacting standards required for research and development. Documentation is available to support regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. The product should be handled under appropriate conditions to maintain its biological activity and integrity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Complies
Purity (SEC-HPLC)	≥95% Monomer
Protein Content	≥1.0 mg/mL (or as per COA)
Endotoxin	<1.0 EU/mg
Biological Activity (ELISA/Bioassay)	Complies with reference standard
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.