Description

2'-Methoxy-5'-(trifluoromethoxy)acetophenone is a specialized aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both methoxy and trifluoromethoxy substituents, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those requiring trifluoromethoxy-substituted aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve lipophilicity and biological activity.
• Material Science Precursor: Serves as a monomer or intermediate for synthesizing specialty polymers and advanced organic materials with specific optical or electronic properties.
• Ligand Synthesis: Utilized in the preparation of complex ligands for catalysis and coordination chemistry applications.
• Chemical Research & Development: A versatile substrate for method development in organic synthesis, including cross-coupling reactions and functional group transformations.

Basic Information

Product Name	2'-Methoxy-5'-(Trifluoromethoxy)Acetophenone
CAS No.	468074-92-2
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	1-[2-Methoxy-5-(trifluoromethoxy)phenyl]ethanone; 2'-Methoxy-5'-(trifluoromethoxy)acetophenone; 1-(2-Methoxy-5-(trifluoromethoxy)phenyl)ethan-1-one; 2-Methoxy-5-(trifluoromethoxy)acetophenone; Acetophenone, 2'-methoxy-5'-(trifluoromethoxy)-; Ethanone, 1-[2-methoxy-5-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 2'-Methoxy-5'-(trifluoromethoxy)acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to reliable supply and documented quality supports your R&D and scale-up processes with confidence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.