Description

1H-Pyrrole-2-Carbonitrile,1-(Fluoromethyl)-5-Methyl-(9Ci) is a specialized fluorinated pyrrole derivative, a high-value chemical intermediate prized for its unique molecular scaffold. This compound matters for its role in constructing complex molecules, particularly in advanced pharmaceutical and agrochemical research where the introduction of fluorine atoms is critical for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluoromethyl group can enhance lipophilicity and biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the research of conductive polymers and advanced organic electronic materials.
• Fluorine Chemistry: An essential reagent for studying structure-activity relationships (SAR) and for introducing fluorinated motifs into complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and reference standards.

Basic Information

Product Name	1H-Pyrrole-2-Carbonitrile,1-(Fluoromethyl)-5-Methyl-(9Ci)
CAS No.	463298-07-9
Molecular Formula	C7H7FN2
Molecular Weight	138.14 g/mol
Synonyms	1-(Fluoromethyl)-5-methyl-1H-pyrrole-2-carbonitrile; 5-Methyl-1-(fluoromethyl)-1H-pyrrole-2-carbonitrile; 1-(Fluoromethyl)-5-methylpyrrole-2-carbonitrile; 1H-Pyrrole-2-carbonitrile, 1-(fluoromethyl)-5-methyl-; 463298-07-9; Pyrrole-2-carbonitrile, 1-(fluoromethyl)-5-methyl-
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2-Carbonitrile,1-(Fluoromethyl)-5-Methyl-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.