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4-Methylumbelliferyl 2-Sulfamino-2-Deoxy-α-D-Glucopyranoside Sodium Salt CAS NO 460085-45-4


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CAS No.:460085-45-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Methylumbelliferyl 2-Sulfamino-2-Deoxy-α-D-Glucopyranoside Sodium Salt is a specialized fluorogenic substrate designed for the sensitive detection and quantification of enzymatic activity. This compound is critical for research and diagnostic applications requiring high specificity and low detection limits. It is primarily utilized by biochemists, pharmaceutical researchers, and diagnostic kit manufacturers in the life sciences sector for enzyme assay development and high-throughput screening.

Application

  • Enzyme Substrate for Sulfatases: Specifically used as a fluorogenic substrate for 2-sulfamido-2-deoxy-α-D-glucosidase and related sulfatase enzymes in biochemical research.
  • Diagnostic Assay Development: A key component in the development of in vitro diagnostic (IVD) kits for detecting enzyme deficiencies or abnormalities.
  • High-Throughput Screening (HTS): Employed in pharmaceutical discovery for screening compound libraries against specific sulfatase targets.
  • Biochemical Research: Used to study enzyme kinetics, inhibition, and mechanism of action in purified enzyme systems or cell lysates.
  • Quality Control in Biomanufacturing: Applied in the quality control testing of enzyme products to verify specific activity and purity.

Basic Information

Product Name 4-Methylumbelliferyl 2-Sulfamino-2-Deoxy-α-D-Glucopyranoside Sodium Salt
CAS No. 460085-45-4
Molecular Formula C₁₆H₁₇NNaO₁₁S
Molecular Weight 462.36 g/mol
Synonyms 4-MU-2S-GlcNAc-6S Sodium Salt; 4-Methylumbelliferyl 2-Sulfamido-2-deoxy-α-D-glucopyranoside Sodium Salt; 4-MU-α-GlcNS Sodium Salt; 2-Sulfamino-2-Deoxy-α-D-Glucopyranoside, 4-Methylumbelliferyl, Sodium Salt; α-4-MU-GlcNS; Fluorogenic substrate for sulfatase; 4-Methylumbelliferyl-α-D-N-sulfoglucosaminide Sodium Salt
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Quality Control

Our 4-Methylumbelliferyl 2-Sulfamino-2-Deoxy-α-D-Glucopyranoside Sodium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive assays. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, desiccate at low temperature. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 95.0%
Assay ≥ 98.0% (on dried basis)
Water Content (KF) ≤ 5.0%
Fluorogenic Activity Functional in standard assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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