Description

3-(3,4-Difluorophenyl)-n-Methylpropan-1-Amine CAS NO 459872-41-4 is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its difluorophenyl moiety can impart desirable metabolic stability and bioavailability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for advanced polymers with specific thermal or chemical resistance properties.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or molecular probes for diagnostic and research applications.

Basic Information

Item	Detail
Product Name	3-(3,4-Difluorophenyl)-n-Methylpropan-1-Amine
CAS No.	459872-41-4
Molecular Formula	C10H13F2N
Molecular Weight	185.21 g/mol
Synonyms	1-(3,4-Difluorophenyl)-3-(methylamino)propane; N-Methyl-3-(3,4-difluorophenyl)propan-1-amine; 3-(3,4-Difluorophenyl)-N-methylpropan-1-amine; 3,4-Difluoro-N-methylhydrocinnamylamine; 459872-41-4; N-Methyl-3-(3,4-difluorophenyl)propylamine; 3-(3,4-Difluorophenyl)-N-methyl-1-propanamine
EINECS	Contact for details

Quality Control

Our 3-(3,4-Difluorophenyl)-n-Methylpropan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.