Description

3-Fluoro-n-Isopropylbenzamide (CAS NO 459218-95-2) is a high-purity fluorinated benzamide derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical and agrochemical research, enabling the introduction of fluorine and amide functionalities to modulate biological activity and physicochemical properties. It is essential for medicinal chemists and process development scientists in the pharmaceutical, crop protection, and fine chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging the fluorine atom for enhanced bioavailability and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Precursor: Employed in the synthesis of fluorinated polymers and liquid crystals with unique electronic and optical properties.
• Chemical Biology Probe: Useful for creating activity-based probes to study enzyme function and protein-ligand interactions.
• Custom Synthesis & Scale-Up: A foundational component for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis projects.

Basic Information

Product Name	3-Fluoro-n-Isopropylbenzamide
CAS No.	459218-95-2
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	3-Fluoro-N-(propan-2-yl)benzamide; N-Isopropyl-3-fluorobenzamide; 3-Fluorobenzoic acid isopropylamide; Benzamide, 3-fluoro-N-(1-methylethyl)-; 459218-95-2; 3-Fluoro-N-isopropyl-benzamide; m-Fluoro-N-isopropylbenzamide
EINECS	Contact for details

Quality Control

Our 3-Fluoro-n-Isopropylbenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.