Description

3-(2-Chlorophenyl)-8-[(Diisobutylamino)Methyl]-7-Hydroxy-2-(Trifluoromethyl)-4H-Chromen-4-One is a high-purity, synthetic chromen-4-one derivative, recognized for its complex molecular architecture featuring a trifluoromethyl group and a diisobutylamino-methyl substituent. This compound is valued in advanced chemical synthesis for its role as a key pharmacophore or intermediate in the development of novel active ingredients. It is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry, agrochemical research, and material science. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique trifluoromethyl and chromenone core.
• Agrochemical Development: Investigated as a precursor for novel active ingredients in crop protection products.
• Biochemical Tool Compound: Employed in biochemical assays to study protein-ligand interactions and cellular mechanisms.
• Material Science Research: Explored for the development of advanced organic materials with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific projects.

Basic Information

Item	Detail
Product Name	3-(2-Chlorophenyl)-8-[(Diisobutylamino)Methyl]-7-Hydroxy-2-(Trifluoromethyl)-4H-Chromen-4-One
CAS No.	459152-44-4
Molecular Formula	C26H27ClF3NO3
Molecular Weight	493.95 g/mol
Synonyms	8-[(Diisobutylamino)methyl]-7-hydroxy-3-(2-chlorophenyl)-2-(trifluoromethyl)-4H-chromen-4-one; 7-Hydroxy-3-(2-chlorophenyl)-8-[(diisobutylamino)methyl]-2-(trifluoromethyl)-4H-1-benzopyran-4-one; 459152-44-4; Chromen-4-one derivative; Trifluoromethyl chromenone intermediate
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Chlorophenyl)-8-[(Diisobutylamino)Methyl]-7-Hydroxy-2-(Trifluoromethyl)-4H-Chromen-4-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.