Description

3-Pyridinepropanenitrile,α-Hydroxy-(9Ci) is a specialized pyridine derivative nitrile compound that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both hydroxy and nitrile functional groups on a pyridine-propane backbone, makes it a versatile building block for constructing complex molecular architectures. This high-purity intermediate is primarily sought after by research institutions and pharmaceutical development teams engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the pyridine moiety is a common structural feature.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Manufacturing: Employed in the multistep synthesis of complex dyes, pigments, and specialty performance chemicals.
• Academic & Industrial Research: A critical reagent for methodological studies in organic synthesis, including C-C bond formation and functional group transformations.

Basic Information

Product Name	3-Pyridinepropanenitrile,α-Hydroxy-(9Ci)
CAS No.	458528-65-9
Molecular Formula	C9H10N2O
Molecular Weight	162.19 g/mol
Synonyms	α-Hydroxy-3-pyridinepropanenitrile; 2-Hydroxy-3-(3-pyridyl)propanenitrile; 3-Pyridinepropanenitrile, α-hydroxy-; (RS)-2-Hydroxy-3-pyridin-3-ylpropionitrile; 3-(2-Hydroxyethyl)pyridine carbonitrile; Hydroxy(pyridin-3-yl)propanenitrile; (3-Pyridyl)-2-hydroxypropionitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinepropanenitrile,α-Hydroxy-(9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.