Description

Benzenepropanenitrile, 3-Fluoro-α-Hydroxy- (9Ci) is a specialized fluorinated aromatic nitrile building block featuring a chiral α-hydroxy group. This compound is valued for its unique molecular architecture, which enables the synthesis of complex, biologically active molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of fluorinated drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated pesticides and herbicides to enhance efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals where fluorine substitution imparts desired thermal and chemical stability.
• Fine Chemical Production: Acts as a versatile building block for custom synthesis and contract manufacturing of high-value specialty chemicals.

Basic Information

Product Name	Benzenepropanenitrile, 3-Fluoro-α-Hydroxy- (9Ci)
CAS No.	458528-62-6
Molecular Formula	C9H8FNO
Molecular Weight	165.17 g/mol
Synonyms	3-Fluoro-α-hydroxybenzenepropanenitrile; 3-Fluoro-2-hydroxy-3-phenylpropionitrile; (RS)-3-Fluoro-2-hydroxy-3-phenylpropionitrile; 2-Hydroxy-3-(3-fluorophenyl)propanenitrile; α-Hydroxy-3-fluorohydrocinnamomitrile; 3-Fluoromandelonitrile; β-(3-Fluorophenyl)-α-hydroxyacetonitrile
EINECS	Contact for details

Quality Control

Our Benzenepropanenitrile, 3-Fluoro-α-Hydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) with full chromatographic data (HPLC/GC) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.