Description

Benzonitrile, 4-Bromo-2-(Bromomethyl)- is a versatile brominated benzonitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the presence of two distinct bromine functionalities, which enable selective and sequential functionalization for constructing complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and materials science applications.
• Functional Material Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers where bromine atoms facilitate cross-coupling reactions.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological systems and mechanisms of action.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical market.

Basic Information

Product Name	Benzonitrile, 4-Bromo-2-(Bromomethyl)-
CAS No.	457051-12-6
Molecular Formula	C8H5Br2N
Molecular Weight	274.94 g/mol
Synonyms	4-Bromo-2-(bromomethyl)benzonitrile; 2-(Bromomethyl)-4-bromobenzonitrile; 4-Bromo-2-bromomethylbenzonitrile; Benzonitrile, 4-bromo-2-(bromomethyl)-; 2,4-Dibromobenzyl cyanide (related but not exact); 4-Bromo-α-bromo-o-tolunitrile
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 4-Bromo-2-(Bromomethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.