Description

2-(2-Fluorophenyl)Cyclopropanecarboxylic Acid is a high-value fluorinated cyclopropane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique structure, combining a cyclopropane ring with a fluorinated aromatic system, makes it indispensable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorinated cyclopropane moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	2-(2-Fluorophenyl)Cyclopropanecarboxylic Acid
CAS No.	455267-56-8
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	2-(2-Fluorophenyl)cyclopropanecarboxylic acid; 2-(2-Fluorophenyl)cyclopropane-1-carboxylic acid; (1R,2S)-rel-2-(2-Fluorophenyl)cyclopropanecarboxylic Acid; (1S,2R)-rel-2-(2-Fluorophenyl)cyclopropanecarboxylic Acid; 2-(o-Fluorophenyl)cyclopropanecarboxylic Acid; 2-(2-Fluorophenyl)-1-cyclopropanecarboxylic Acid; 2-Fluorophenylcyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorophenyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.