Description

n-Boc-2-Naphthylamine is a protected amine derivative of 2-naphthylamine, serving as a crucial Boc-protected aromatic amine building block in organic synthesis. This compound matters for its role in facilitating complex multi-step syntheses where selective amine protection and deprotection are required. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing active pharmaceutical ingredients (APIs), ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating complex amine-containing heterocycles.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the naphthylamine scaffold provides specific biological activity.
• Material Science: Serves as a monomer or functionalization agent in the production of specialty polymers, dyes, and photoactive materials.
• Academic & Contract Research: Essential reagent in medicinal chemistry and methodology research for exploring new synthetic pathways.
• Peptidomimetics: Employed in the design and synthesis of peptide analogs and conformationally constrained scaffolds.
• Ligand Preparation: Useful for synthesizing nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	n-Boc-2-Naphthylamine
CAS No.	454713-45-2
Molecular Formula	C15H17NO2
Molecular Weight	243.30 g/mol
Synonyms	tert-Butyl (naphthalen-2-yl)carbamate; 2-[(tert-Butoxycarbonyl)amino]naphthalene; N-(tert-Butoxycarbonyl)-2-naphthylamine; N-Boc-2-Aminonaphthalene; Boc-2-Naphthylamine; 2-Naphthylamine, N-Boc-protected; N-(2-Naphthyl)carbamic acid tert-butyl ester; 2-(Boc-amino)naphthalene
EINECS	Contact for details

Quality Control

Our n-Boc-2-Naphthylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.