Description

1,5-Anhydro-2,6-Dideoxy-4-o-(4,5-Difluoro-2-Hydroxyphenyl)-6-(Diphenylphosphinyl)-D-Arabino-Hexitol is a sophisticated, high-purity synthetic intermediate featuring a unique combination of a modified sugar backbone with fluorinated aromatic and phosphinyl functional groups. This compound is valued for its role in advanced pharmaceutical research and development, particularly in the synthesis of novel bioactive molecules and potential drug candidates. It is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require specialized building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), especially for fluorinated compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the fluorinated phenyl and phosphinyl groups confer specific biological activity.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study enzyme mechanisms or biological pathways due to its phosphoryl group.
• Chiral Catalyst or Ligand Synthesis: The complex stereochemistry makes it a potential precursor for synthesizing chiral ligands used in asymmetric catalysis.
• Glycomimetics Research: Used in the study and synthesis of carbohydrate mimics (glycomimetics) for therapeutic applications.
• Academic & Institutional R&D: Employed in university and government laboratories for fundamental research in organic and medicinal chemistry.

Basic Information

Product Name	1,5-Anhydro-2,6-Dideoxy-4-o-(4,5-Difluoro-2-Hydroxyphenyl)-6-(Diphenylphosphinyl)-D-Arabino-Hexitol
CAS No.	454475-43-5
Molecular Formula	C24H23F2O5P
Molecular Weight	460.41 g/mol
Synonyms	4,5-Difluoro-2-hydroxyphenyl 1,5-anhydro-2,6-dideoxy-6-(diphenylphosphinyl)-D-arabino-hexitol; 1,5-Anhydro-2,6-dideoxy-4-O-(4,5-difluoro-2-hydroxyphenyl)-6-(diphenylphosphinyl)-D-arabino-hexitol; D-Arabino-Hexitol, 1,5-anhydro-2,6-dideoxy-4-O-(4,5-difluoro-2-hydroxyphenyl)-6-(diphenylphosphinyl)-; 454475-43-5; Fluorinated Phosphinyl Sugar Derivative; Difluorophenyl Phosphinyl Anhydrohexitol
EINECS	Contact for details

Quality Control

Our 1,5-Anhydro-2,6-Dideoxy-4-o-(4,5-Difluoro-2-Hydroxyphenyl)-6-(Diphenylphosphinyl)-D-Arabino-Hexitol is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; ensure it is stored separately from such materials. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.