Description

3-([(4-Chlorophenyl)Sulfonyl]Methyl)-4-(1H-Pyrrol-1-Yl)Benzenecarbonitrile is a high-value, multi-functional organic intermediate designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, which incorporates a chlorophenylsulfonyl group, a pyrrole moiety, and a benzonitrile unit, enabling its use in constructing complex target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of its sulfonyl and nitrile functional groups.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialized polymers, dyes, or organic electronic materials.
• Chemical Biology Probe Synthesis: Employed to create molecular tools and probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-([(4-Chlorophenyl)Sulfonyl]Methyl)-4-(1H-Pyrrol-1-Yl)Benzenecarbonitrile
CAS No.	454473-77-9
Molecular Formula	C18H13ClN2O2S
Molecular Weight	356.83 g/mol
Synonyms	4-(1H-Pyrrol-1-yl)-3-[[(4-chlorophenyl)sulfonyl]methyl]benzonitrile; 3-((4-Chlorophenylsulfonyl)methyl)-4-(1H-pyrrol-1-yl)benzonitrile; Benzonitrile, 4-(1H-pyrrol-1-yl)-3-[[(4-chlorophenyl)sulfonyl]methyl]-; 454473-77-9; 3-[(4-Chlorobenzene-1-sulfonyl)methyl]-4-(1H-pyrrol-1-yl)benzonitrile
EINECS	Contact for details

Quality Control

Our 3-([(4-Chlorophenyl)Sulfonyl]Methyl)-4-(1H-Pyrrol-1-Yl)Benzenecarbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP standards ensures reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.