Description

1,1,1-Trifluoro-3-(2-Trifluoromethyl-Benzylamino)-Propan-2-Ol is a specialized fluorinated organic compound featuring a benzylamino-propanol core structure. This molecule is valued for its unique chemical properties derived from the strategic placement of multiple fluorine atoms and a reactive amino alcohol group, making it a versatile building block in advanced synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, or as protease inhibitors.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a sophisticated intermediate for creating fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Employed to introduce fluorine-containing functional groups into polymer chains, imparting properties like oil/water repellency, chemical resistance, and low surface energy.
• Organic Synthesis & Catalysis Research: Acts as a valuable reagent or ligand precursor in academic and industrial research exploring new fluorination methodologies or asymmetric catalysis.
• Material Science Research: Investigated for developing specialty coatings, surfactants, and other performance materials that benefit from fluorine's unique characteristics.

Basic Information

Product Name	1,1,1-Trifluoro-3-(2-Trifluoromethyl-Benzylamino)-Propan-2-Ol
CAS No.	453557-79-4
Molecular Formula	C12H12F6NO
Molecular Weight	300.22 g/mol
Synonyms	1,1,1-Trifluoro-3-[(2-(trifluoromethyl)phenyl)methylamino]propan-2-ol; 2-Propanol, 1,1,1-trifluoro-3-[[[2-(trifluoromethyl)phenyl]methyl]amino]-; 3-((2-(Trifluoromethyl)benzyl)amino)-1,1,1-trifluoropropan-2-ol; α-(Trifluoromethyl)benzylamino trifluoro isopropanol; TFMP-BAPA; CAS 453557-79-4
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-3-(2-Trifluoromethyl-Benzylamino)-Propan-2-Ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by HPLC), impurity profile, and physical characterization. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its chemical nature as a fluoride/strong alkali-sensitive compound, it should be kept separate from incompatible materials. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.