Description

(1S,2S)-2-(Diphenylphosphino)-1-Aminocyclohexane, Min. 97% is a high-purity, chiral bidentate ligand featuring both phosphine and amine donor groups. This compound matters for its exceptional ability to induce stereoselectivity in transition metal-catalyzed reactions, a critical factor in producing enantiomerically pure intermediates. It is primarily needed by research chemists and process development scientists in the pharmaceutical and fine chemical industries for applications such as asymmetric hydrogenation and cross-coupling.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically pure pharmaceutical intermediates.
• Catalyst component in asymmetric C-C bond forming reactions, including cross-couplings and additions.
• Key reagent for the development of novel transition metal catalysts used in academic and industrial research.
• Use in the synthesis of optically active compounds for agrochemicals and specialty materials.
• Employed in methodology development for stereoselective transformations in process chemistry.

Basic Information

Product Name	(1S,2S)-2-(Diphenylphosphino)-1-Aminocyclohexane, Min. 97%
CAS No.	452304-63-1
Molecular Formula	C18H22NP
Molecular Weight	283.35 g/mol
Synonyms	(1S,2S)-(-)-1-Amino-2-(diphenylphosphino)cyclohexane; (1S,2S)-2-(Diphenylphosphino)cyclohexanamine; (1S,2S)-Cyclohexane-1,2-diamine, 2-(diphenylphosphino)-; (S,S)-2-(Diphenylphosphino)-1-aminocyclohexane; (S,S)-Cyclohexanediamino diphenylphosphine; (S,S)-DACH-phenyl Trost Ligand precursor; (1S,2S)-DACH-PPh2; (S,S)-DPPACH
EINECS	Contact for details

Quality Control

Our (1S,2S)-2-(Diphenylphosphino)-1-Aminocyclohexane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure a minimum purity of 97% and correct stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent performance in sensitive catalytic applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C. The material is easily oxidized and light-sensitive; prolonged exposure to air or ambient light should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Chiral Purity (HPLC)	Min. 99.0% ee
Water Content (KF)	Max. 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.