Description

(1R,2R)-2-(Diphenylphosphino)-1-Aminocyclohexane, Min. 97% is a high-purity chiral ligand and organocatalyst belonging to the class of P,N-donor ligands. This compound is essential for enabling highly selective and efficient asymmetric transformations in fine chemical and pharmaceutical synthesis. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic routes and optimizing production processes.

Application

• Asymmetric Hydrogenation: A key chiral ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, crucial for producing single-enantiomer active pharmaceutical ingredients (APIs).
• Asymmetric C-C Bond Formation: Catalyzes enantioselective cross-coupling, allylic substitution, and addition reactions to construct complex chiral molecules.
• Pharmaceutical Intermediate Synthesis: Used in the development and scale-up of chiral intermediates for drugs targeting CNS disorders, cardiovascular diseases, and infectious diseases.
• Agrochemical Synthesis: Employed in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Catalyst Screening & Development: A valuable tool in high-throughput screening (HTS) and catalyst discovery programs within R&D laboratories.
• Academic & Industrial Research: Serves as a fundamental building block in methodological studies and the development of new catalytic systems in organic chemistry.

Basic Information

Product Name	(1R,2R)-2-(Diphenylphosphino)-1-Aminocyclohexane, Min. 97%
CAS No.	452304-59-5
Molecular Formula	C18H22NP
Molecular Weight	283.35 g/mol
Synonyms	(1R,2R)-(-)-1-Amino-2-(diphenylphosphino)cyclohexane; (1R,2R)-2-(Diphenylphosphino)cyclohexanamine; (R,R)-2-(Diphenylphosphino)-1-aminocyclohexane; (R,R)-DACH-Phenyl; (1R,2R)-DACH-Phenyl; (R,R)-1-Amino-2-(diphenylphosphino)cyclohexane; (1R,2R)-1-Amino-2-diphenylphosphinocyclohexane; (R,R)-CyclohexaneDiamine-based Phosphine Ligand
EINECS	Contact for details

Quality Control

Our (1R,2R)-2-(Diphenylphosphino)-1-Aminocyclohexane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the specified minimum 97% purity and consistent performance. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be purged with inert gas before resealing after each use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Chiral Purity (Chiral HPLC)	Min. 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.