Description

N,n-Di-tert-Butoxycarbonyl-Benzene-1,2-Diamine is a high-purity, protected diamine derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular control in the development of complex molecules. It is primarily utilized in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and in advanced material science for creating specialty polymers and ligands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocycles and active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Peptide Mimetics & Linker Chemistry: Used to introduce protected diamine functionalities into peptide backbones and as a versatile linker in bioconjugation and prodrug strategies.
• Ligand Synthesis for Catalysis: Serves as a starting material for the preparation of chiral and achiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Resin Modification: Employed to functionalize polymers and resins, imparting specific chemical reactivity or physical properties for advanced material applications.
• Agrochemical Research: Acts as an intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for constructing molecular libraries in high-throughput screening.

Basic Information

Product Name	N,n-Di-tert-Butoxycarbonyl-Benzene-1,2-Diamine
CAS No.	452077-13-3
Molecular Formula	C₁₆H₂₄N₂O₄
Molecular Weight	308.37 g/mol
Synonyms	1,2-Phenylenediamine, N,N-bis(tert-butoxycarbonyl)-; N,N-Bis-Boc-1,2-phenylenediamine; N,N-Bis(tert-butoxycarbonyl)benzene-1,2-diamine; N,N-Di-Boc-o-phenylenediamine; Bis-Boc-o-phenylenediamine; 1,2-Diaminobenzene N,N-di-Boc derivative; N1,N2-Bis(tert-butoxycarbonyl)benzene-1,2-diamine
EINECS	Contact for details

Quality Control

Our N,n-Di-tert-Butoxycarbonyl-Benzene-1,2-Diamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.