Description

Carbamic Acid, [(1R,2R)-2-(Phenylthio)Cyclohexyl]-, 1,1-Dimethylethyl Ester, Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecules with precise three-dimensional architecture, which is essential for developing novel pharmaceuticals and agrochemicals. Pharmaceutical R&D and fine chemical manufacturers need this material for the synthesis of active pharmaceutical ingredients (APIs), particularly in projects targeting neurological and metabolic disorders where stereochemistry is crucial for efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and metabolic disease targets.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to introduce the (1R,2R)-2-(phenylthio)cyclohexyl moiety into complex molecular frameworks.
• Agrochemical Research: Serves as a precursor in the development of new, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Catalyst Ligand Development: Potential utility in the synthesis of novel chiral ligands for asymmetric catalysis.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies in organic and medicinal chemistry.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of chiral drugs.

Basic Information

Product Name	Carbamic Acid, [(1R,2R)-2-(Phenylthio)Cyclohexyl]-, 1,1-Dimethylethyl Ester, Rel- (9Ci)
CAS No.	450410-78-3
Molecular Formula	C17H25NO2S
Molecular Weight	307.45 g/mol
Synonyms	tert-Butyl N-[(1R,2R)-2-(phenylsulfanyl)cyclohexyl]carbamate; (1R,2R)-N-(tert-Butoxycarbonyl)-2-(phenylthio)cyclohexanamine; rel-(1R,2R)-2-(Phenylthio)cyclohexylcarbamic Acid tert-Butyl Ester; tert-Butyl ((1R,2R)-2-(phenylthio)cyclohexyl)carbamate; BOC-Protected (1R,2R)-2-(Phenylthio)cyclohexylamine; (1R,2R)-2-(Phenylthio)cyclohexylamine N-BOC derivative
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1R,2R)-2-(Phenylthio)Cyclohexyl]-, 1,1-Dimethylethyl Ester, Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical identity, typically meeting standards suitable for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability and chiral integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.