Description

3,5-Bis(Trifluoromethyl)Phenylsulfonylethanol is a high-value fluorinated building block characterized by its unique sulfonylethanol functional group attached to a bis(trifluoromethyl)phenyl core. This compound matters for its role as a versatile intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the introduction of fluorine atoms and sulfone groups is critical for modulating properties like metabolic stability, lipophilicity, and electronic characteristics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced performance profiles.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in areas requiring fluorinated motifs for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl groups contribute to biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, or organic electronic materials to alter surface energy and optical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Phenylsulfonylethanol
CAS No.	450409-87-7
Molecular Formula	C10H8F6O3S
Molecular Weight	322.22 g/mol
Synonyms	2-[3,5-Bis(trifluoromethyl)phenyl]sulfonyl-1-ethanol; 1-[3,5-Bis(trifluoromethyl)phenyl]sulfonyl-2-ethanol; 3,5-Bis(trifluoromethyl)benzenesulfonylethanol; 2-Hydroxyethyl 3,5-bis(trifluoromethyl)phenyl sulfone; α-Hydroxyethyl 3,5-bis(trifluoromethyl)phenyl sulfone; (2-Hydroxyethylsulfonyl)-1,3-bis(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoromethyl)Phenylsulfonylethanol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.