Description

3Ah-Indene-3A-Carbonitrile,Octahydro-1-Hydroxy-1-Methyl-7-Methylene-,(1R,3Ar,7As)-Rel-(9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex, polycyclic structure containing hydroxyl, nitrile, and methylene groups makes it a valuable chiral building block for constructing pharmacologically active molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel, high-value target compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex, polycyclic drug candidates.
• Agrochemical Synthesis: Used as a building block in the development of novel pesticides and herbicides, leveraging its unique carbon skeleton for bioactivity.
• Organic Synthesis Research: Employed in academic and industrial R&D labs for methodological studies, including cyclization reactions and stereoselective transformations.
• Fine Chemical Production: Acts as a key intermediate in the multi-step synthesis of specialty chemicals and complex natural product analogs.
• Ligand and Catalyst Development: Its functional groups can be modified to create novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	3Ah-Indene-3A-Carbonitrile,Octahydro-1-Hydroxy-1-Methyl-7-Methylene-,(1R,3Ar,7As)-Rel-(9Ci)
CAS No.	450406-27-6
Molecular Formula	C12H17NO
Molecular Weight	191.27 g/mol
Synonyms	(1R,3aR,7aS)-rel-Octahydro-1-hydroxy-1-methyl-7-methylene-1H-indene-3a-carbonitrile; rel-(1R,3aR,7aS)-Octahydro-1-hydroxy-1-methyl-7-methylene-1H-indene-3a-carbonitrile; 1H-Indene-3a-carbonitrile, octahydro-1-hydroxy-1-methyl-7-methylene-, (1R,3aR,7aS)-rel-; 450406-27-6; (1R,3aR,7aS)-1-Hydroxy-1-methyl-7-methyleneoctahydro-1H-indene-3a-carbonitrile
EINECS	Contact for details

Quality Control

Our 3Ah-Indene-3A-Carbonitrile,Octahydro-1-Hydroxy-1-Methyl-7-Methylene-,(1R,3Ar,7As)-Rel-(9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.