Description

1,2-Cyclopropanedicarboxylicacid,1-(Acetylamino)-,(1R,2S)-Rel-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where precise stereochemistry is critical for biological activity. Pharmaceutical research organizations and fine chemical manufacturers need this material for constructing complex molecular architectures, particularly in the synthesis of novel therapeutic agents and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), especially in areas requiring constrained, cyclopropane-based scaffolds.
• Asymmetric Synthesis: Utilized as a building block in stereoselective chemical reactions to introduce the 1,2-disubstituted cyclopropane motif with defined absolute configuration.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced crop protection agents and herbicides that leverage its unique three-membered ring structure.
• Ligand and Catalyst Development: Used in the preparation of novel chiral ligands and organocatalysts for applications in homogeneous catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific mechanical or optical properties.

Basic Information

Item	Details
Product Name	1,2-Cyclopropanedicarboxylicacid,1-(Acetylamino)-,(1R,2S)-Rel-(9Ci)
CAS No.	446879-45-4
Molecular Formula	C8H11NO5
Molecular Weight	201.18 g/mol
Synonyms	(1R,2S)-1-Acetamidocyclopropane-1,2-dicarboxylic Acid; rel-(1R,2S)-1-(Acetylamino)cyclopropane-1,2-dicarboxylic Acid; 1-Acetamidocyclopropane-1,2-dicarboxylic Acid (rel-(1R,2S)-); (1R,2S)-rel-1-(Acetylamino)cyclopropane-1,2-dicarboxylic Acid; 1,2-Cyclopropanedicarboxylic acid, 1-(acetylamino)-, (1R,2S)-rel-; Chiral Cyclopropane Amino Acid Derivative
EINECS	Contact for details

Quality Control

Our 1,2-Cyclopropanedicarboxylicacid,1-(Acetylamino)-,(1R,2S)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with customer specifications and high industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.