Description

Boc-Amino-(3-Bromophenyl)Acetic Acid is a protected amino acid derivative, specifically a tert-butoxycarbonyl (Boc) protected building block featuring a 3-bromophenyl side chain. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering controlled reactivity for the construction of biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development, particularly for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used to incorporate a brominated aromatic moiety into peptide backbones, enabling the study of structure-activity relationships (SAR) and the development of enzyme inhibitors.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled or modified peptides used as probes in biochemical and cellular assays.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery campaigns.
• Agrochemical Research: Potential intermediate in the development of novel peptide-inspired crop protection agents.

Basic Information

Item	Details
Product Name	Boc-Amino-(3-Bromophenyl)Acetic Acid
CAS No.	446305-66-4
Molecular Formula	C₁₃H₁₆BrNO₄
Molecular Weight	330.18 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-bromophenylglycine; (3-Bromophenyl)((tert-butoxycarbonyl)amino)acetic acid; Boc-3-Br-Phg-OH; Boc-(3-Bromophenyl)glycine; N-Boc-3-bromophenylglycine; 2-((tert-Butoxycarbonyl)amino)-2-(3-bromophenyl)acetic acid; BOC-AMINO-(3-BROMO-PHENYL)-ACETIC ACID
EINECS	Contact for details

Quality Control

Our Boc-Amino-(3-Bromophenyl)Acetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.